RECRUITINGOBSERVATIONAL
Comparing the Diagnostic Sensitivity and Specificity of Pleural Fluid N-Terminal Pro B-type Natriuretic Peptide (NT-proBNP) and Other Biochemical Gradient Criteria in Distinguishing Heart Failure and Non-heart Failure Related Pleural Effusions (CENTRE Study)
Comparing N-terminal-proB-type Natriuretic Peptide with Other Diagnostic Criteria in Discriminating Heart Failure-associated from Non-heart Failure-associated Pleural Effusions
About This Trial
To assess the discriminative properties of pleural fluid (PF) N-terminal-proB-type-natriuretic-peptide (NTproBNP) levels in identifying heart failure (HF)-associated pleural effusions (PE).
Who May Be Eligible (Plain English)
Who May Qualify:
- Patients hospitalized for heart failure and pleural effusion
- Pleural tapping indicated for pleural fluid analysis.
- Aged 18 years old or above
Who Should NOT Join This Trial:
- History of intrapleural therapy (including talc and fibrinolytic) in the ipsilateral pleural space.
- History of surgical decortication or pleurodesis in the ipsilateral pleural space.
- Ipsilateral thoracic or cardiac surgery in the past 3 months.
- Failure to obtain willing to sign a consent form due to the patient's refusal or cognitive impairment.
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Patients hospitalized for heart failure and pleural effusion
* Pleural tapping indicated for pleural fluid analysis.
* Aged 18 years old or above
Exclusion Criteria:
* History of intrapleural therapy (including talc and fibrinolytic) in the ipsilateral pleural space.
* History of surgical decortication or pleurodesis in the ipsilateral pleural space.
* Ipsilateral thoracic or cardiac surgery in the past 3 months.
* Failure to obtain informed consent due to the patient's refusal or cognitive impairment.
Locations (1)
Prince of Wales Hospital
Hong Kong, New Territories, Hong Kong