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RECRUITINGINTERVENTIONAL

Cohort of STEMI Patients 2

CoHort of Patients to Identify Biological and Imaging markerS of CardiovascUlar Outcomes in ST Elevation Myocardial Infarction

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

ST-segment elevation myocardial infarction (STEMI) is an acute condition that accounts for 75% of sudden deaths in adults over 35 years of age and more than half of all cases of chronic heart failure. However, the mechanism of myocardial infarction remains poorly understood. At present, there is no national information system for myocardial infarction, as there is for other diseases such as multiple sclerosis (OFSEP cohort). The purpose of this cohort is to enable studies and research projects to be carried out on the descriptive epidemiology of myocardial infarction, monitoring of patients undergoing treatment (safety, efficacy), quality of life and functional consequences of infarction, and research into new biological and imaging prognostic biomarkers. Its general objective is to provide researchers, hospital practitioners, medical interns, academics or industrialists with a quality epidemiological tool for research.

Who May Be Eligible (Plain English)

Who May Qualify: - Age ≥ 18 years - Diagnosis of STEMI defined by ST segment elevation ≥ 0.2 mV in 2 contiguous leads on a 12-lead ECG. - Management in primary ACT - Prior oral willing to sign a consent form followed by signed willing to sign a consent form as soon as possible. Who Should NOT Join This Trial: - Diagnosis of STEMI not confirmed on angiography - Inability to give the subject informed information - Lack of coverage by a social security scheme - Obvious contraindication to injected magnetic resonance imaging (claustrophobia, pacemaker, defibrillator, or a metallic body (ferromagnetic), severe renal insufficiency (GFR\<30 ml/min), known allergy to the contrast medium ....) - Pregnant woman or woman of childbearing age without effective contraception, breastfeeding woman. - Deprivation of civil rights (curators, guardianship, safeguard of justice) Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Age ≥ 18 years * Diagnosis of STEMI defined by ST segment elevation ≥ 0.2 mV in 2 contiguous leads on a 12-lead ECG. * Management in primary ACT * Prior oral informed consent followed by signed informed consent as soon as possible. Exclusion Criteria: * Diagnosis of STEMI not confirmed on angiography * Inability to give the subject informed information * Lack of coverage by a social security scheme * Obvious contraindication to injected magnetic resonance imaging (claustrophobia, pacemaker, defibrillator, or a metallic body (ferromagnetic), severe renal insufficiency (GFR\<30 ml/min), known allergy to the contrast medium ....) * Pregnant woman or woman of childbearing age without effective contraception, breastfeeding woman. * Deprivation of civil rights (curators, guardianship, safeguard of justice)

Treatments Being Tested

OTHER

MRI

1 MRI at 1 month with gadolinium injection

BIOLOGICAL

Biocollection

Biocollection from blood (H0, H4, H24, H48, 1 month, 1 year), urine (H48) and faecal (initial hospitalisation) samples.

BEHAVIORAL

Quality of life questionaries

EQ-5D-5L and HAD questionaries at 1 month and 1 year.

Locations (2)

Hospices Civils de Lyon - Hôpital Louis Pradel
Bron, Rhone, France
Hospices Civils de Lyon - Hôpital de la Croix Rousse
Lyon, Rhone, France