RECRUITINGOBSERVATIONAL
Prognosis of Cerebral Small Vessel Disease
Prognosis of Cerebral Small Vessel Disease - a Prospective Cohort Study (PRO-SVD)
About This Trial
Prognosis of small vessel disease (SVD) depends on the underlying type of SVD and index manifestation. The aim of this prospective, observational cohort study is to determine the risk of different outcome events among patients with SVD according to the type of index presentation.
Who May Be Eligible (Plain English)
Who May Qualify:
- Hypertensive deep perforator arteriolopathy (DPA), clinically symptomatic with either ICH, ischaemic stroke, cognitive impairment or severe radiological manifestation (Fazekas ≥II)
- Cerebral amyloid angiopathy (CAA according to modified Boston or Edinburgh criteria), clinically symptomatic with either ICH (including cSAH), amyloid spells, cognitive impairment or severe radiological manifestation (CMB≥2)
- Other SVD (i.e. CADASIL or other sporadic or genetic SVD)
Who Should NOT Join This Trial:
- Life expectancy of \<6 months due to not-SVD related causes (i.e. cancer)
- Patient is unlikely to attend follow-up visits
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Hypertensive deep perforator arteriolopathy (DPA), clinically symptomatic with either ICH, ischaemic stroke, cognitive impairment or severe radiological manifestation (Fazekas ≥II)
* Cerebral amyloid angiopathy (CAA according to modified Boston or Edinburgh criteria), clinically symptomatic with either ICH (including cSAH), amyloid spells, cognitive impairment or severe radiological manifestation (CMB≥2)
* Other SVD (i.e. CADASIL or other sporadic or genetic SVD)
Exclusion Criteria:
* Life expectancy of \<6 months due to not-SVD related causes (i.e. cancer)
* Patient is unlikely to attend follow-up visits
Locations (1)
Department of Neurology, Inselspital Bern University Hospital
Bern, Switzerland