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RECRUITINGOBSERVATIONAL

Volatile Non-Invasive Biomarkers of Epileptic Seizures

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

Breath and sweat samples will be collected from people who have been admitted to hospital after a potential seizure and analysed by the team. The researchers then hope to identify a pattern of small molecules that can distinguish seizures from other events, and perhaps determine the severity of the seizure.

Who May Be Eligible (Plain English)

Who May Qualify: 1. Patients who have been admitted to either University College London's Queen's Square EEG-telemetry unit or Chalfont Centre for Epilepsy, for diagnosis of seizure events. 2. Patients aged 18 years or above Who Should NOT Join This Trial: 1. Patients with active infection or who have taken antibiotics within 4 weeks 2. Patients on immunosuppressive medications 3. Patients with co-morbidities preventing breath collection 4. Patients unable to provide willing to sign a consent form. Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: 1. Patients who have been admitted to either University College London's Queen's Square EEG-telemetry unit or Chalfont Centre for Epilepsy, for diagnosis of seizure events. 2. Patients aged 18 years or above Exclusion Criteria: 1. Patients with active infection or who have taken antibiotics within 4 weeks 2. Patients on immunosuppressive medications 3. Patients with co-morbidities preventing breath collection 4. Patients unable to provide informed consent.

Treatments Being Tested

OTHER

Sample Collection

Patients will have breath samples collected by blowing into a bag, and sweat samples collected by gauze. These samples will be collected at various timepoints whilst the patients are admitted on the ward.

Locations (2)

Chalfont Centre for Epilepsy
London, Buckinghamshire, United Kingdom
National Hospital for Neurology and Neurosurgery
London, London, United Kingdom