RECRUITINGOBSERVATIONAL
Longitudinal Assessment of Brain Structure and Function in Juvenile-onset Huntington's Disease
Longitudinal Assessment of Brain Structure and Function in Juvenile Onset Huntington's Disease (JoHD)
About This Trial
The goal of this observational study is to learn about brain development in Juvenile-onset Huntington's Disease (JoHD). The main questions it aims to answer are: * Is brain development different in JoHD than Adult-onset Huntington's Disease (AoHD)? * Can reliable biomarkers for JoHD be found in brain structure and function? Participants will be asked to complete cognitive tests, behavioral assessments, physical and neurologic evaluation, and MRI. Data collected will be compared to populations who are at-risk for HD and who have been diagnosed with HD as adults.
Who May Be Eligible (Plain English)
Who May Qualify:
- Clinical diagnosis of JoHD
- Aged 6-30
Who Should NOT Join This Trial:
- Metal in body
- History of head trauma, brain tumor, seizures or epilepsy unrelated to JoHD
- History of major surgery or serious chronic medical conditions other than JoHD
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Clinical diagnosis of JoHD
* Aged 6-30
Exclusion Criteria:
* Metal in body
* History of head trauma, brain tumor, seizures or epilepsy unrelated to JoHD
* History of major surgery or serious chronic medical conditions other than JoHD
Locations (6)
University of California Davis
Sacramento, California, United States
University of Iowa Hospitals and Clinics, Department of Psychiatry
Iowa City, Iowa, United States
Columbia University Medical Center
New York, New York, United States
Children's Hospital of Philadelphia with the University of Pennsylvania
Philadelphia, Pennsylvania, United States
Vanderbilt University Medical Center
Nashville, Tennessee, United States
University of Texas Health Science Center at Houston
Houston, Texas, United States