Skip to main content
TrialFinder
TrialFinder is for informational purposes only and does not provide medical advice. Always talk to your doctor about whether a trial is right for you.
RECRUITINGPhase 4INTERVENTIONAL

Optimizing Evidence-based HIV Prevention Targeting People Who Inject Drugs on PrEP

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The investigators will conduct an optimization trial among N=256 PWID newly started on medication for opioid use disorder and Pre-Exposure Prophylaxis (PrEP) to assess the performance of four intervention components (Attention, Executive Functioning, Memory, and Information Processing) aimed at enhancing the ability of PWID on MOUD to process and utilize HIV prevention content, leading to improvements in HIV prevention information, motivation, behavioral skills, and behaviors (IMB).

Who May Be Eligible (Plain English)

Who May Qualify: - being 18 years or older - meeting DSM-V criteria for opioid dependence and being newly prescribed and adherent to Medication for Opioid Use Disorder (e.g., methadone, buprenorphine) at the APT Foundation, Inc. - showing mild cognitive impairment based on the Montreal Cognitive Assessment (MoCA) screening - having initiated Pre-Exposure Prophylaxis (PrEP) within the past week - confirming HIV-negative status through proof of PrEP prescription - reporting unsafe injection drug use practices or unprotected sex within the past 3 months - having a cell phone - being able to read and understand in English Who Should NOT Join This Trial: - unable to provide consent - actively suicidal - actively homicidal - actively psychotic - display MoCA scores suggestive of dementia Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * being 18 years or older * meeting DSM-V criteria for opioid dependence and being newly prescribed and adherent to Medication for Opioid Use Disorder (e.g., methadone, buprenorphine) at the APT Foundation, Inc. * showing mild cognitive impairment based on the Montreal Cognitive Assessment (MoCA) screening * having initiated Pre-Exposure Prophylaxis (PrEP) within the past week * confirming HIV-negative status through proof of PrEP prescription * reporting unsafe injection drug use practices or unprotected sex within the past 3 months * having a cell phone * being able to read and understand in English Exclusion Criteria: * unable to provide consent * actively suicidal * actively homicidal * actively psychotic * display MoCA scores suggestive of dementia

Treatments Being Tested

BEHAVIORAL

community-friendly health recovery program

Participants will receive 4 weekly 45 minute sessions HIV prevention sessions.

DRUG

Pre-Exposure Prophylaxis and Post-Exposure Prophylaxis

Participants will be prescribed Pre-exposure prophylaxis (PrEP) is a biomedical intervention.

Locations (1)

APT Foundation
New Haven, Connecticut, United States