RECRUITINGOBSERVATIONAL

Characterization of Arrhythmia-induced Cardiomyopathy

Arrhythmia-induced Cardiomyopathy - a Prospective Observational Cohort Study

About This Trial

The goal of the this observational study is to gather clinically available data on patients presenting with a suspicion for arrhythmia-induced cardiomyopathy (AiCM) at the University Hospital Basel.

Who May Be Eligible (Plain English)

Prospective part Who May Qualify: - Diagnostic or suspicion of AiCM as presence of specified keyword in patient's file or as screened by colleagues of the internal medicine or cardiology clinics - Signed study consent Who Should NOT Join This Trial: - Patient's active refusal of the general consent of the University Hospital Basel - Age \<18 years old - Temporary Who Should NOT Join This Trial: Acute health condition such as myocardial infarction, patients presenting with a major trauma, a sepsis, patients shortly after cardiac surgery, and patients in shock (\>100 bpm, \<90 systolic BP, evidence of organ dysfunction). - Life expectancy \<1 year (palliative, terminal cancer) Retrospective part Who May Qualify: - Patients with a reduced left-ventricular ejection fraction (LVEF ≤50%) or a reduction of 15% in the ejection fraction (EF) between two echocardiographies and a concomitant diagnosis of any arrhythmia likely to lead to AiCM within one year before or after diagnosis of the reduced LVEF from 2010-2021 Who Should NOT Join This Trial: - Age \< 18 years old - Patient's active refusal of the general consent of the University Hospital Basel - Acute event clearly leading to an acutely reduced LVEF (massive type I myocardial infarction, cardiogenic shock from a coronary or myocardial etiology, septic shock leading to toxic myopathy, hypovolemic shock with reduced EF, cardiac arrest and/or need for resuscitation). - Patients with life expectancy \<1 year (palliative, terminal cancer) Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language

Prospective part Inclusion Criteria: * Diagnostic or suspicion of AiCM as presence of specified keyword in patient's file or as screened by colleagues of the internal medicine or cardiology clinics * Signed study consent Exclusion Criteria: * Patient's active refusal of the general consent of the University Hospital Basel * Age \<18 years old * Temporary exclusion criteria: Acute health condition such as myocardial infarction, patients presenting with a major trauma, a sepsis, patients shortly after cardiac surgery, and patients in shock (\>100 bpm, \<90 systolic BP, evidence of organ dysfunction). * Life expectancy \<1 year (palliative, terminal cancer) Retrospective part Inclusion Criteria: * Patients with a reduced left-ventricular ejection fraction (LVEF ≤50%) or a reduction of 15% in the ejection fraction (EF) between two echocardiographies and a concomitant diagnosis of any arrhythmia likely to lead to AiCM within one year before or after diagnosis of the reduced LVEF from 2010-2021 Exclusion Criteria: * Age \< 18 years old * Patient's active refusal of the general consent of the University Hospital Basel * Acute event clearly leading to an acutely reduced LVEF (massive type I myocardial infarction, cardiogenic shock from a coronary or myocardial etiology, septic shock leading to toxic myopathy, hypovolemic shock with reduced EF, cardiac arrest and/or need for resuscitation). * Patients with life expectancy \<1 year (palliative, terminal cancer)

Treatments Being Tested

OTHER

Data collection: Major adverse cardiovascular event (MACE) assessment questionnaire (prospective part)

Data collection: Major adverse cardiovascular event (MACE) assessment questionnaire (prospective part). The assessment will be done via mail, letter or phone

OTHER

Data collection: Quality of Life (QoL) Questionnaire (prospective part)

Data collection: Quality of Life (QoL) Questionnaire (prospective part). The questionnaire "EQ-5D-5L questionnaire" will be used to assess quality of life.

OTHER

Data collection (retrospective study)

Anonymized search and review of patients electronic health records of the University Hospital of Basel for patients with a reduced LVEF and a concomitant (±1year or after any observation of a reduced LVEF in imaging) diagnosis of arrhythmia known to be causing AiCM.

OTHER

Data collection (prospective study database)

Data collection on alcohol consumption, family history, rhythm disorder, hospitalizations, cardiac assessments, adverse events at baseline, 6 months, 1 year, 2 years and 5 years.

Locations (1)

University Hospital Basel, Department of Cardiology

Basel, Switzerland