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RECRUITINGOBSERVATIONAL

Hemodynamic Stability in Septic Shock Patients Undergoing Continuous Renal Replacement Therapy With oXiris Membrane

Real-time Monitoring of Hemodynamic Stability in Septic Shock Patients Undergoing Continuous Renal Replacement Therapy: Propensity Score-matched Comparison Between oXiris and Polysulfone Membranes

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The new adsorbing membrane for continuous renal replacement therapy (CRRT), oXiris, can reduce plasma cytokines and endotoxins in septic shock patients with severe acute kidney injury, compared with standard membranes. However, its hemodynamic stability or benefits have not been thoroughly evaluated although this is reasonable.

Who May Be Eligible (Plain English)

Who May Qualify: - Aged ≥ 18 years - Sepsis related acute kidney injury requiring continuous renal replacement therapy Who Should NOT Join This Trial: • No monitoring of blood pressure and ECG Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Aged ≥ 18 years * Sepsis related acute kidney injury requiring continuous renal replacement therapy Exclusion Criteria: • No monitoring of blood pressure and ECG

Treatments Being Tested

DEVICE

oXiris membrane

Perform continuous renal replacement therapy with oXiris membrane

DEVICE

Polysulfone membrane

Perform continuous renal replacement therapy with polysulfone membrane

Locations (1)

Seoul National University Hospital
Seoul, South Korea