Avalus European Registry - an Observational Study to Evaluate Safety and Efficacy in a Real World Population

Who May Qualify: - Clinical indication for replacement of the native or prosthetic aortic valve with a bioprosthesis - Age \>= 18 years - Patient has been adequately informed of risks and requirements of the registry (which are actually limited since the prosthesis is in full commercial use and only data registration is performed) and is able to provide willing to sign a consent form for participation in the clinical registry. Who Should NOT Join This Trial: - Patient requires salvage surgery (according to EuroSCORE II definitions: "patients requiring cardiopulmonary resuscitation (external cardiac massage) en route to the operating theatre or prior to induction of anaesthesia. This does not include cardiopulmonary resuscitation following induction of anaesthesia") - Not been able to provide willing to sign a consent form Always talk to your doctor about whether this trial is right for you.