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RECRUITINGOBSERVATIONAL

A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Pallidotomy for the Treatment of Advanced, Idiopathic Parkinson's Disease With Medication-refractory Moderate to Severe Motor Complications

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

This registry is a prospective, multicenter, international, single arm, observational post-approval registry with follow-up at 3, 6, and 12 months, and annually for 5 years. The proposed registry will enroll 60 subjects and will be conducted at approximately 10 centers worldwide.

Who May Be Eligible (Plain English)

Who May Qualify: - Men and women, age 30 years and older. - Subject undergoing a planned an Exablate procedure for their Parkinson's Disease with Motor Complications per local institution standard of care. - Subject is willing to cooperate with the Registry requirements including compliance with the regimen and completion of all Registry visits. - Subject has signed and received a copy of the approved willing to sign a consent form form. Who Should NOT Join This Trial: - Subject does not agree to participate or is unlikely to participate for the entirety of the Registry. Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Men and women, age 30 years and older. * Subject undergoing a planned an Exablate procedure for their Parkinson's Disease with Motor Complications per local institution standard of care. * Subject is willing to cooperate with the Registry requirements including compliance with the regimen and completion of all Registry visits. * Subject has signed and received a copy of the approved informed consent form. Exclusion Criteria: * Subject does not agree to participate or is unlikely to participate for the entirety of the Registry.

Treatments Being Tested

DEVICE

Exablate Pallidotomy, Unilateral

Unilateral pallidotomy using focused ultrasound for the treatment of Parkinson's Disease with medication-refractory moderate to severe motor complications.

Locations (5)

University of Maryland, Baltimore
Baltimore, Maryland, United States
Weill Cornell Medicine
New York, New York, United States
University of Pennsylvania
Philadelphia, Pennsylvania, United States
University of Texas Southwestern Medical Center
Dallas, Texas, United States
Ohnishi Neurological Center
Akashi, Hyōgo, Japan