Drug Discovery for Parkinson's With Mutations in the GBA Gene

Who May Qualify: - Age 18 years or older. - Diagnosis of Parkinson's disease, Gaucher disease, or healthy control. - Must provide written willing to sign a consent form unless physical limitations preclude signing. Who Should NOT Join This Trial: - For skin samples collected specifically for this study: history of keloid formation, coagulation disorder, allergy to the anesthetic, or anticoagulation use that precludes sample collection. - For blood samples collected specifically for this study: coagulation disorder or other medical condition(s) that increases the risks associated with blood collection. - For all prospective sample collections: Subjects who refuse to adhere to NYSCF's and/or a collection site's safety protocols will be excluded. Subjects with an AIDS diagnosis and CD4 count of less than 200 cells per microliter (mcL) of blood will be excluded due to increased risk of infection. Always talk to your doctor about whether this trial is right for you.