RECRUITINGOBSERVATIONAL
Endoscopic Radiofrequency Ablation of Celiac Ganglion for Pain Management and Improvement of Quality of Life in Patients With Unresectable Pancreatic Cancer
Endoscopic Ultrasound-guided Radiofrequency Ablation of Celiac Ganglion for Pain Management and Improvement of Quality of Life in Patients With Unresectable Pancreatic Cancer
About This Trial
This study aims to evaluate the EUS-RFA in terms of efficacy for pain management and improvement in quality-of-life parameters for patients with advanced inoperable pancreatic cancer. The primary objectives of this study are to 1) evaluate the utility of EUS-RFA for pain control and improvement in quality-of-life parameters for patients with advanced pancreatic cancer; 2) to measure the reduction of analgesic medications' requirements in patients affected by inoperable pancreatic cancer.
Who May Be Eligible (Plain English)
Who May Qualify:
- Diagnosis of pancreatic cancer based on clinical, radiological, or pathological assessment;
- Referred for abdominal and/or back pain due to pancreatic cancer;
- No prior history of RFA;
- Cancer pain unresponsive to the WHO 3-step analgesic ladder;
- Willingness to consent to participate in the study.
Who Should NOT Join This Trial:
- Patients who are not willing to give willing to sign a consent form or agree to participate in the study
- Surgically resectable pancreatic cancer;
- Abdominal pain with etiology other than pancreatic malignancy;
- Evidence of concurrent infection;
- Patients with irreversible coagulopathy international normalized ratio \>1.5 or platelet count \<50,000/mm3),
- Patients with a preliminary diagnosis of adenocarcinoma are not possible established with intraprocedural at EUS-guided FNA.
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Diagnosis of pancreatic cancer based on clinical, radiological, or pathological assessment;
* Referred for abdominal and/or back pain due to pancreatic cancer;
* No prior history of RFA;
* Cancer pain unresponsive to the WHO 3-step analgesic ladder;
* Willingness to consent to participate in the study.
Exclusion Criteria:
* Patients who are not willing to give informed consent or agree to participate in the study
* Surgically resectable pancreatic cancer;
* Abdominal pain with etiology other than pancreatic malignancy;
* Evidence of concurrent infection;
* Patients with irreversible coagulopathy international normalized ratio \>1.5 or platelet count \<50,000/mm3),
* Patients with a preliminary diagnosis of adenocarcinoma are not possible established with intraprocedural at EUS-guided FNA.
Treatments Being Tested
PROCEDURE
Ablation of Celiac Ganglion
Endoscopic Ultrasound-guided Radiofrequency Ablation of Celiac Ganglion
Locations (1)
Shailendra Singh
Morgantown, West Virginia, United States