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RECRUITINGOBSERVATIONAL

Value of Pleural Lavage Cytology in Resectable Esophageal Carcinoma Eastern Cooperative Thoracic Oncology Projects 2005, ECTOP-2005)

A Prospective Study for Pleural Lavage Cytology in Patients With Esophageal Cancer

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

Disease recurrence and metastasis are common after curative treatment for patients with esophageal cancer. Thus, it is important to identify the risk factors to predict disease recurrence and metastasis. Pleural lavage cytology (PLC) is reported to be associated with disease recurrence and patient survival in lung cancer, but the value is unclear in esophageal cancer. The aim of this study is to evaluate the value of PLC in esophageal cancer patient in terms of frequencies, association with patient survival, and efficacy of postoperative treatment.

Who May Be Eligible (Plain English)

Who May Qualify: - esophageal cancer with histological confirmation before treatment. - resectable esophageal cancer with clinical T1-4a/N0-3/M0 staging - potential R0 resection - no history of other malignancies Who Should NOT Join This Trial: - severe major organ dysfunction (American society of anesthesiologisits score \>3 ) - patients underwent ESD or EMR - pleural lavage is unavailable due to adhesions Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * esophageal cancer with histological confirmation before treatment. * resectable esophageal cancer with clinical T1-4a/N0-3/M0 staging * potential R0 resection * no history of other malignancies Exclusion Criteria: * severe major organ dysfunction (American society of anesthesiologisits score \>3 ) * patients underwent ESD or EMR * pleural lavage is unavailable due to adhesions

Treatments Being Tested

OTHER

pleural lavage

pleural lavages before tumor resection and after tumor resecion, respectively

Locations (11)

The First Affiliated Hospital of USTC
Hefei, Anhui, China
The Fourth Hospital of Hebei Medical University
Shijiazhuang, Hebei, China
Henan Provincial People's Hospital
Zhengzhou, Henan, China
Nantong Tumor Hospital
Nantong, Jiangsu, China
The Second Affiliated Hospital of Nantong University
Nantong, Jiangsu, China
Taixing People's Hospital
Taishing, Jiangsu, China
Taizhou People's Hospital
Taizhou, Jiangsu, China
Shaanxi Provincial cancer Hospital
Xi'an, Shaanxi, China
The First Affiliated Hospital of Xi'an Jiaotong University
Xi'an, Shannxi, China
Tianjin Medical University Cancer Institute
Tianjin, Tianjin Municipality, China
Fudan University Shanghai Cancer Center
Shanghai, China