RECRUITINGOBSERVATIONAL

Evaluation of Ablation Lesions Using Cardiovascular Magnetic Resonance Imaging

About This Trial

Ineffective ablation lesions can cause arrhythmia recurrence after catheter ablation for cardiac arrhythmia. Ablation lesions can be created with various ablation energy modalities. This study uses cardiovascular magnetic resonance imaging to evaluate the ablation lesion characteristics of radiofrequency ablation, ultra-low temperature cryo ablation, and pulsed field ablation. The ablation lesion characteristics of different energy characteristics will be compared. Additionally, arrhythmia recurrence and quality of life will be evaluated for the different energy modalities.

Who May Be Eligible (Plain English)

Who May Qualify: - Adult patients (age ≥18 years old) - Paroxysmal or persistent atrial fibrillation, meeting criteria of the 2020 European Society of Cardiology Guidelines for diagnosis and management of atrial fibrillation - Patients scheduled to undergo catheter ablation for cardiac arrhythmia using one of the following techniques: Radiofrequency ablation (High power, short duration), Ultra-low temperature cryo ablation, or Pulsed field ablation Who Should NOT Join This Trial: - Known (or suspected) allergic reaction to gadolinium - Contraindications for MRI (such as claustrophobia, certain implants, devices, high body mass index). - Pregnancy or breastfeeding - Prior intervention in the left atrium (ablation or surgery) Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language

Inclusion Criteria: * Adult patients (age ≥18 years old) * Paroxysmal or persistent atrial fibrillation, meeting criteria of the 2020 European Society of Cardiology Guidelines for diagnosis and management of atrial fibrillation * Patients scheduled to undergo catheter ablation for cardiac arrhythmia using one of the following techniques: Radiofrequency ablation (High power, short duration), Ultra-low temperature cryo ablation, or Pulsed field ablation Exclusion Criteria: * Known (or suspected) allergic reaction to gadolinium * Contraindications for MRI (such as claustrophobia, certain implants, devices, high body mass index). * Pregnancy or breastfeeding * Prior intervention in the left atrium (ablation or surgery)

Treatments Being Tested

DEVICE

Catheter ablation

An ablation catheter is introduced in the heart. Ablation is performed by applying ablation energy to the target tissue. The aim of ablation is to create an ablation lesion that does not conduct the electrical signals that induce or sustain the cardiac arrhythmia.

Locations (1)

St. Antonius Hospital

Nieuwegein, Netherlands