RECRUITINGINTERVENTIONAL
Diagnostic Yield of Intranodal Forceps Biopsies in Mediastinal Adenopathy
Evaluating the Diagnostic Yield and Specimen Quality With Endobronchial Ultrasound-Guided Intranodal Forceps Biopsies in Patients With Mediastinal and Hilar Lymphadenopathy: A Prospective Analysis
About This Trial
The investigators will compare endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) with intranodal forceps biopsy (EBUS-IFB) as it relates to the rate of diagnosis of suspected sarcoidosis.
Who May Be Eligible (Plain English)
Who May Qualify:
- Radiologic evidence of mediastinal and/or hilar lymphadenopathy
- Attending radiologist or pulmonologist reports a possible diagnosis of sarcoidosis
- Age 18 years or older
Exclusion Criteria\*:
These are the characteristics that a participant must NOT have in order to be eligible to participate in the study.
Order Number Criteria
- Severe pulmonary hypertension
- Inability to undergo general anesthesia
- Severe coagulopathy or bleeding diathesis
- Previously diagnosed sarcoidosis
- Patient presently taking clopidogrel
- Patient deemed to be high risk for general anesthesia per anesthesiologist
- Hemodynamic instability
- Mediastinitis
- Acute Hypercarbic Respiratory Failure (pCO2 \>55mmHg)
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Radiologic evidence of mediastinal and/or hilar lymphadenopathy
* Attending radiologist or pulmonologist reports a possible diagnosis of sarcoidosis
* Age 18 years or older
Exclusion Criteria\*:
These are the characteristics that a participant must NOT have in order to be eligible to participate in the study.
Order Number Criteria
* Severe pulmonary hypertension
* Inability to undergo general anesthesia
* Severe coagulopathy or bleeding diathesis
* Previously diagnosed sarcoidosis
* Patient presently taking clopidogrel
* Patient deemed to be high risk for general anesthesia per anesthesiologist
* Hemodynamic instability
* Mediastinitis
* Acute Hypercarbic Respiratory Failure (pCO2 \>55mmHg)
Treatments Being Tested
PROCEDURE
Endobronchial Ultrasound-Guided Intranodal Forceps Biopsy
Patients with mediastinal adenopathy will undergo EBUS-IFB and EBUS-TBNA during the same procedure to compare the yield of this procedure with EBUS-TBNA alone.
Locations (1)
The George Washington University Hospital
Washington D.C., District of Columbia, United States