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RECRUITINGOBSERVATIONAL

South Asians and Coronary Plaque Registry

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

Individuals who self-report as SAs will be recruited to participate in this registry as well as non-SA controls for comparison. All individuals who consent to participate will 1) complete a survey assessing demographics, medical history, family medical history; 2) have blood collection; 3) and CCTA assessment. These data will be combined with clinical data from the electronic health record and, if applicable, the Dallas Hearts and Mind Study and other research studies, for research purposes. The registry will serve to generate primary observations as well as preliminary data for future studies.

Who May Be Eligible (Plain English)

Who May Qualify: - Males and Females: Age 18 years or above - South Asian (SA) adults through self-identification (South Asians to have both biological parents with ancestry from India, Pakistan, Sri Lanka, Nepal and Bangladesh) - We also propose to enroll an equivalent number of individuals of other descent as a comparator group (Non SA Adult Volunteers) - Sampling Method: Probability Sample Who Should NOT Join This Trial: - Under the age of 18 years - Unable to give willing to sign a consent form - Impaired renal function: estimated glomerular filtration rate ≤ 45ml/min - Baseline heart rate≥70 bpm or ≥66 bpm after beta blocker - Body mass index (BMI) of 35 or greater - Prior anaphylactic/non-anaphylactic reaction or other contraindication to iodinated contrast - Anyone who cannot do CCTA for any reason - Pregnancy Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Males and Females: Age 18 years or above * South Asian (SA) adults through self-identification (South Asians to have both biological parents with ancestry from India, Pakistan, Sri Lanka, Nepal and Bangladesh) * We also propose to enroll an equivalent number of individuals of other descent as a comparator group (Non SA Adult Volunteers) * Sampling Method: Probability Sample Exclusion Criteria: * Under the age of 18 years * Unable to give informed consent * Impaired renal function: estimated glomerular filtration rate ≤ 45ml/min * Baseline heart rate≥70 bpm or ≥66 bpm after beta blocker * Body mass index (BMI) of 35 or greater * Prior anaphylactic/non-anaphylactic reaction or other contraindication to iodinated contrast * Anyone who cannot do CCTA for any reason * Pregnancy

Treatments Being Tested

DIAGNOSTIC_TEST

Coronary CT Angiogram

A computerized tomography (CT) coronary angiogram is non-invasive imaging test that looks at the arteries that supply blood to your heart.

Locations (1)

University of Texas Southwestern Medical Center
Dallas, Texas, United States