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RECRUITINGOBSERVATIONAL

Selective CT for Anticoagulated Head Injured Patients

Selective Neuroimaging for Head-injured Emergency Patients Who Take Anticoagulant Medication

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The goal is to derive and a clinical decision rule for safe exclusion of traumatic brain injury without neuroimaging in head-injured ED patients who take anticoagulant medications. The objectives are to: 1. Derive and externally validate a new highly sensitive and maximally specific clinical decision rule for the exclusion of traumatic brain injury in head-injured ED patients who take anticoagulant medications; and, 2. Estimate the sensitivity and specificity of existing head injury clinical decision rules in head-injured ED patients who take anticoagulant medications.

Who May Be Eligible (Plain English)

Who May Qualify: - Age ≥16 years - Presents to the emergency department after a head injury - Patient has a head CT in the emergency department - Is a current anticoagulant user Who Should NOT Join This Trial: - Head injury occurred \>48 h before patient's arrival to the emergency department - Penetrating head injury - Previously enrolled - Patient resides outside of the hospital's catchment area - Patient was transferred from another emergency department following neuroimaging - Patient was not managed by the emergency or trauma physician in the emergency department - Leaves the emergency department prior to completion of their medical assessment Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Age ≥16 years * Presents to the emergency department after a head injury * Patient has a head CT in the emergency department * Is a current anticoagulant user Exclusion Criteria: * Head injury occurred \>48 h before patient's arrival to the emergency department * Penetrating head injury * Previously enrolled * Patient resides outside of the hospital's catchment area * Patient was transferred from another emergency department following neuroimaging * Patient was not managed by the emergency or trauma physician in the emergency department * Leaves the emergency department prior to completion of their medical assessment

Locations (7)

University of British Columbia
Vancouver, British Columbia, Canada
Hamilton Health Sciences Corporation
Hamilton, Ontario, Canada
Kingston Health Sciences Centre
Kingston, Ontario, Canada
Ottawa Hospital Research Institute
Ottawa, Ontario, Canada
Sinai Health
Toronto, Ontario, Canada
Hôpital du Sacré-Cœur de Montréal
Montreal, Quebec, Canada
CHU de Québec - Université Laval
Québec, Quebec, Canada