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RECRUITINGINTERVENTIONAL

Infusion Set Replacement Intervals for Critically Ill Patients

Effect of Infusion Set Replacement Intervals on Central Line-associated Bloodstream Infection in Adult Intensive Care Unit: a Multicenter Randomised Clinical Trial

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

This study aimed to evaluate the efficacy of 24-hour versus 96-hour infusion set replacement to prevent central line-associated bloodstream infection (CLABSI) in critically ill adults with central venous access devices.

Who May Be Eligible (Plain English)

Who May Qualify: 1. Age 18 years or older 2. Able to provide willing to sign a consent form 3. Expected length of stay (LOS) \> 96 hours in intensive care unit (ICU) 4. Need for treatment with central venous access device 5. The central venous access device is expected to remain in place for at least 96 hours, with infusion set attached Who Should NOT Join This Trial: 1. Those who with a bloodstream infection within the previous 48 hours after ICU admission 2. Those who have their vascular access device actually removed within 96 hours after ICU admission 3. Those who have participated in other clinical studies within the 2 months Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: 1. Age 18 years or older 2. Able to provide informed consent 3. Expected length of stay (LOS) \> 96 hours in intensive care unit (ICU) 4. Need for treatment with central venous access device 5. The central venous access device is expected to remain in place for at least 96 hours, with infusion set attached Exclusion Criteria: 1. Those who with a bloodstream infection within the previous 48 hours after ICU admission 2. Those who have their vascular access device actually removed within 96 hours after ICU admission 3. Those who have participated in other clinical studies within the 2 months

Treatments Being Tested

PROCEDURE

Infusion set replacement intervals

24-hour or 96-hour infusion set replacement intervals

Locations (1)

Zhongnan Hospital of Wuhan University
Wuhan, Hubei, China