Diet and Meal Timing in Patients With Metabolic Dysfunction Associated Steatoic Liver Disease

Who May Qualify: - Age ≥ 18 and \< 65 years old - Must provide signed written willing to sign a consent form and agree to comply with the study protocol - BMI \>25 kg/m² - Baseline liver fat content of at least 10% as measured by MRI-PDFF Who Should NOT Join This Trial: - Unclear etiology of liver disease - Competing etiologies for hepatic steatosis - Co-existing causes of chronic liver disease according to standard diagnostic testing including, but not restricted to: - Positive hepatitis B surface antigen - Positive hepatitis C virus RNA - Suspicion of drug-induced liver disease - Alcoholic liver disease - Autoimmune hepatitis - Wilson's disease - Hemochromatosis - Primary biliary cholangitis or primary sclerosing cholangitis - Known or suspected hepatocellular carcinoma - Current or recent history (\<5 years) of significant alcohol consumption. For men, significant consumption is defined as \>30g of alcohol per day. For women, it is defined as \>20g of alcohol per day. - Compensated and decompensated cirrhosis (clinical and/or histologic evidence of cirrhosis). NASH patients with fibrosis stage = 4 according to the NASH CRN fibrosis staging system are excluded. - Reduction in weight by ≥ 5% within the prior 90 days - Current fasting for ≥ 12 hours per day on the majority of days each week - Pregnant females - Mental instability or incompetence, such that the validity of the willing to sign a consent form or ability to be compliant with the study is uncertain - Inability to perform MRI-PDFF and/or study as defined below - Inability to medically perform prolonged fasting (i.e. insulin regimen) Always talk to your doctor about whether this trial is right for you.