Study on the Effect of 40 Hz Non-Invasive Light Therapy System
ALZLIGHT Stage III - Study on the Effect of 40 Hz Non-Invasive Light Therapy System
About This Trial
The ALZLIGHT STAGE III Study is a continuation of the ALZLIGHT Pilot - Study on Safety, Feasibility and Neural Activation of Non-Invasive Light Therapy System. As with the first two stages, this study will examine whether entrainment of 40 Hz neural oscillation by novel 40 Hz Invisible Spectral Flicker is a potential therapy for Alzheimer's Disease. In order to examine this, 62 patients with mild to moderate Alzheimer's Disease will be recruited. The patients will be exposed to the Non-Invasive Light Therapy System for 1 hour a day for 6 months. The effect will be measured by a combination of electroencephalography, cognitive testing, functional magnetic resonance imaging, magnetic resonance spectroscopy and actigraphy.
Who May Be Eligible (Plain English)
Original Eligibility Criteria
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Treatments Being Tested
Light Therapy System (LTS): Active Setting
Exposure for 1 hour á day for consecutive days
Light Therapy System (LTS): Sham Setting
Exposure for 1 hour á day for consecutive days