The Role of Circadian Factors in Regulation of Neuroplasticity in Ischemic Stroke (Observational)

Who May Qualify: - acute (symptom onset to admission \<1 days) ischemic stroke - ischemic stroke affecting the branches of anterior cerebral artery, middle cerebral artery and posterior cerebral artery - age 18-80 years - moderate or severe stroke (National Institutes of Health Stroke Scale, NIHSS\>=5) - intravascular stroke treatment with thrombolysis or thrombectomy leading to satisfactory reperfusion (if applicable) - willing to sign a consent form Who Should NOT Join This Trial: - secondary parenchymal hemorrhage (\>hemorrhage index -2) - clinically unstable or life-threatening conditions - known progressive neurological diseases - known psychiatric diseases - concomitant benzodiazepine medication - drug or alcohol abuse - pregnancy - disability to participate in the study - congestive heart failure with reduced ejection fraction (\<=45%) or New York Heart Association (NYHA) classification III-IV functional class Always talk to your doctor about whether this trial is right for you.