Monoclonal Antibody Duration of REsponse in MIgraine After Treatment Interruption
Monoclonal Antibody Duration of REsponse in MIgraine After Treatment Interruption: A Prospective National Study
About This Trial
Observational analytic study with a prospective cohort design. Patients with episodic and chronic migraine that have responded to monoclonal antibodies (mAbs) versus calcitonin gene-related peptide (CGRP) or its receptor with positive response will be included. A headache diary will be completed in a daily basis. The primary outcome will be the time elapsed between the discontinuation of the monoclonal antibody and the return to the clinical situation at the moment of the mAbs onset. The potential variables that may be associated with a more sustained benefit will be explored.
Who May Be Eligible (Plain English)
Original Eligibility Criteria
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Treatments Being Tested
Headache calendar completion
The patient will complete an in-paper or electronic calendar, depicting the presence/absence of headache, the median intensity and the need of acute medication.