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RECRUITINGINTERVENTIONAL

Evaluation of DNA Methylation Signatures for the Diagnosis and Management of Thyroid Nodules

Evaluation of DNA Methylation Signatures in Diagnosis and Management of Thyroid Nodules

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

This clinical trial evaluates deoxyribonucleic acid (DNA) methylation signatures in diagnosing and managing thyroid nodules. The purpose of this research is to develop a new test for thyroid cancer. This test will use needle biopsies (small collections of tissue with a needle) from the thyroid to determine whether the participant has a malignant (cancer) or benign (not showing cancer) thyroid tumor. The information learned from this trial may help develop a more accurate test so that patients do not have unnecessary surgeries for nodules that are thought to be suspicious but are actually benign.

Who May Be Eligible (Plain English)

Who May Qualify: - Patients without impaired decision-making capacity and who are undergoing needle biopsies for thyroid nodule diagnosis - Over the age of 18 - Any gender, race and ethnicity - Patients must provide willing to sign a consent form prior to use of their tissues and clinical data Who Should NOT Join This Trial: - Children are excluded from the study, since the biology of children thyroid nodules is different from adults Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Patients without impaired decision-making capacity and who are undergoing needle biopsies for thyroid nodule diagnosis * Over the age of 18 * Any gender, race and ethnicity * Patients must provide informed consent prior to use of their tissues and clinical data Exclusion Criteria: * Children are excluded from the study, since the biology of children thyroid nodules is different from adults

Treatments Being Tested

PROCEDURE

Diagnostic Procedure

Analysis via DDMS-2

OTHER

Electronic Health Record Review

Review of medical records

PROCEDURE

Needle Biopsy

Undergo needle biopsy

Locations (1)

City of Hope Medical Center
Duarte, California, United States