RECRUITINGINTERVENTIONAL

Exercise and the Menstrual Cycle in Type 1 Diabetes

Effects of the Menstrual Cycle on Blood Glucose Changes During Exercise in Women With Type 1 Diabetes Using Oral Contraceptives

About This Trial

Female participants with type 1 diabetes using oral contraceptives will be asked to wear a continuous glucose monitor for at least three days on two separate occasions (once during the last week of active pills and once during the no pill/placebo pill phase of the menstrual cycle). An exercise session (45 minutes of aerobic exercise at 60% VO2peak on a cycle ergometer) will take place at 5 pm on the second day of glucose monitoring.

Who May Be Eligible (Plain English)

Who May Qualify: - type 1 diabetes diagnosed for at least 1 year - regular menses - using monophasic oral contraceptives - residing in Edmonton, Alberta and able to visit the lab at the University of Alberta Who Should NOT Join This Trial: - HbA1c \> 9.9% - frequent and unpredictable hypoglycemia - change in insulin management strategy within two months of the study - use of an automated insulin delivery system - blood pressure \> 140/95 - history of cardiovascular disease - severe peripheral neuropathy - active proliferative retinopathy - use of medications (other than insulin) that would affect blood glucose levels - any musculoskeletal condition that would contraindicate exercise (e.g. sprain, strain, joint injury, etc.) Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language

Inclusion Criteria: * type 1 diabetes diagnosed for at least 1 year * regular menses * using monophasic oral contraceptives * residing in Edmonton, Alberta and able to visit the lab at the University of Alberta Exclusion Criteria: * HbA1c \> 9.9% * frequent and unpredictable hypoglycemia * change in insulin management strategy within two months of the study * use of an automated insulin delivery system * blood pressure \> 140/95 * history of cardiovascular disease * severe peripheral neuropathy * active proliferative retinopathy * use of medications (other than insulin) that would affect blood glucose levels * any musculoskeletal condition that would contraindicate exercise (e.g. sprain, strain, joint injury, etc.)

Treatments Being Tested

BEHAVIORAL

Luteal Phase Aerobic Exercise

Participants will perform 45 minutes of moderate (60% VO2peak) aerobic exercise on a cycle ergometer during the last week of active pill consumption.

BEHAVIORAL

Follicular Phase Aerobic Exercise

Participants will perform 45 minutes of moderate (60% VO2peak) aerobic exercise on a cycle ergometer within 5 days of starting their menses.

Locations (1)

Alberta Diabetes Institute

Edmonton, Alberta, Canada