Real Time Vital Sign Assessment to Predict Neurological Decline After Traumatic Brain Injury

Who May Qualify: - Arrival to the hospital within 6 hours of injury - Age \>= 18 years old - Patients with traumatic brain injury(TBI). TBI is defined as any alteration or loss of consciousness with or without positive head C.T findings. Who Should NOT Join This Trial: - Deemed to have a non-survivable TBI - Brain dead on arrival - Active substance abuse for opiates and cocaine as noted by admission toxicology screen. - Any thoracic or abdominal injury resulting in open surgical intervention - Pregnancy - Prisoners - Active military - Non - English speaking (due to necessity for consent in aims 2 and 3) - Age \> 89 years Always talk to your doctor about whether this trial is right for you.