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RECRUITINGINTERVENTIONAL

Understanding Motivation in Parkinson's Patients Through Neurophysiology

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The study aims to better understand motivation and value-based decision-making in Parkinson's patients through neurophysiology using Medtronic's Percept DBS device. By combining behavioral tasks with neural recordings, the study seeks to uncover how DBS affects motivation, particularly in relation to effort, reward, and timing.

Who May Be Eligible (Plain English)

Who May Qualify: - Has Parkinson's Disease or Dystonia - Has Medtronic Percept or RC+S DBS device implanted in either GPI or STN - Has DBS device implanted either bilaterally or unilaterally - Male or female - More than 1 month post-DBS surgery Who Should NOT Join This Trial: - Severe cognitive impairments - Has MOCA score below 20 - Pregnancy - Age less than 18 years old Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Has Parkinson's Disease or Dystonia * Has Medtronic Percept or RC+S DBS device implanted in either GPI or STN * Has DBS device implanted either bilaterally or unilaterally * Male or female * More than 1 month post-DBS surgery Exclusion Criteria: * Severe cognitive impairments * Has MOCA score below 20 * Pregnancy * Age less than 18 years old

Treatments Being Tested

OTHER

Stimulation on

Stimulation from Percept DBS will be on while the patient is playing a decision-making game on a computer-based application.

OTHER

Stimulation off

Stimulation from Percept DBS will be off while the patient is playing a decision-making game on a computer-based application.

BEHAVIORAL

Decision Making Task

Patients will be playing a decision making task through a computer-based application.

Locations (1)

University of California San Francisco
San Francisco, California, United States