Pilot Study of Pancreatic Cancer Screening

Who May Qualify: Ability to provide consent and willing, and able to comply with study procedures Ability to read and speak English GROUP I: - Documentation of pathogenic or likely pathogenic germline BRCA 1 and 2, ATM or PALB2 germline genetic mutation - No strong family history of pancreatic cancer (defined as having \>= 1 first-degree or second-degree relative with a history of pancreatic cancer) - Age \>= 50 years old at time of consent. GROUP II: - Documentation of pathogenic or likely pathogenic germline BRCA 1 and 2, ATM, or PALB2 germline genetic mutation - Has strong family history of pancreatic cancer (defined as having \>= 1 first-degree or second-degree relative with a history of pancreatic cancer) - Age \>= 18 years old at time of consent (screening generally begins 10 years prior to the earliest pancreatic cancer in the family) Who Should NOT Join This Trial: - Prior or active pancreatic cancer. - Pregnant women are excluded from this study because effects of an MRI on developing fetus is unknown. Always talk to your doctor about whether this trial is right for you.