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RECRUITINGOBSERVATIONAL

Neurocognitive Outcomes After Whole Brain Radiation Therapy for Hematologic Malignancies

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

This study assesses neurocognitive outcomes after receiving radiation therapy to the brain (whole brain radiation therapy) in patients with blood cancers (hematologic malignancies). This may help researchers learn more about the effects of whole brain radiation therapy on memory and thinking in patients with blood cancer.

Who May Be Eligible (Plain English)

Who May Qualify: - Age 18 years or older - Treatment with radiation therapy to the brain for a hematologic malignancy (ex. primary central nervous system lymphoma \[PCNSL\], secondary central nervous system lymphoma \[SCNSL\], leukemia, myeloma) - Proficient and capable of completing tests in English - Patients with claustrophobia are eligible if the claustrophobia is managed with medication - Patients with cognitively-impairment are eligible if the impairment is managed with medication - Patients who are pregnant Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Age 18 years or older * Treatment with radiation therapy to the brain for a hematologic malignancy (ex. primary central nervous system lymphoma \[PCNSL\], secondary central nervous system lymphoma \[SCNSL\], leukemia, myeloma) * Proficient and capable of completing tests in English * Patients with claustrophobia are eligible if the claustrophobia is managed with medication * Patients with cognitively-impairment are eligible if the impairment is managed with medication * Patients who are pregnant

Treatments Being Tested

PROCEDURE

Magnetic Resonance Imaging

Undergo MRI

OTHER

Neurocognitive Assessment

Undergo neurocognitive function assessment

OTHER

Quality-of-Life Assessment

Complete questionnaires

OTHER

Questionnaire Administration

Complete questionnaires

Locations (1)

M D Anderson Cancer Center
Houston, Texas, United States