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RECRUITINGINTERVENTIONAL

Time Restricted Feeding, Muscle, and Metabolism

Time Restricted Feeding Intervention for Muscle and Metabolic Health (TRIMM)

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

Effective nutrition strategies for combatting and/or preventing obesity still need to be identified. This has been the case despite the numerous and different approaches that have been taken. Potential targets for combatting/preventing obesity have been identified, but long-term solutions have not emerged. This study uses time restricted feeding to study the role of dietary protein in obesity prevention and/or treatment. The objectives are to determine the role of skeletal muscle mass as a driver of energy-sensing mechanisms and peripheral signals that regulate appetite and energy intake in overweight and obese adults and to determine the effects of protein timing on muscle mass to regulate appetite and energy intake in overweight and obese adults.

Who May Be Eligible (Plain English)

Who May Qualify: - Resides in Northwest Arkansas - Age 25-50 years - BMI \> 25 - All ethnicities - Female and male Who Should NOT Join This Trial: - Food allergies - Pregnant or breastfeeding - Dietary restrictions (e.g. vegetarian, vegan, etc.) - Trying to lose weight in last 3 months - Pre-existing health conditions related to obesity (e.g. cardiovascular disease, diabetes, hypertension) - Prescription medications related to heart disease or type 2 diabetes - Fear of needles - Smoker or vaping - Currently taking protein supplements or other nutritional supplements which may interfere with study outcomes - Consumes \>4 alcoholic beverages per week Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Resides in Northwest Arkansas * Age 25-50 years * BMI \> 25 * All ethnicities * Female and male Exclusion Criteria: * Food allergies * Pregnant or breastfeeding * Dietary restrictions (e.g. vegetarian, vegan, etc.) * Trying to lose weight in last 3 months * Pre-existing health conditions related to obesity (e.g. cardiovascular disease, diabetes, hypertension) * Prescription medications related to heart disease or type 2 diabetes * Fear of needles * Smoker or vaping * Currently taking protein supplements or other nutritional supplements which may interfere with study outcomes * Consumes \>4 alcoholic beverages per week

Treatments Being Tested

DIETARY_SUPPLEMENT

Whey protein supplement

Participants consume whey protein at the beginning of the eating period.

DIETARY_SUPPLEMENT

Ketogenic aid

Participants consume ketogenic aid upon waking.

OTHER

Control group - time restricted feeding only

Time restricted feeding.

Locations (1)

University of Arkansas
Fayetteville, Arkansas, United States