Young Houston Emergency Opioid Engagement System

Who May Qualify: - In otherwise good health based on physician assessment and medical history - Drug screen positive for opioids - Patients express a willingness to stop opioid use - Meet Diagnostic and Statistical Manual of Mental Disorders - Text Revision (DSM-IV-TR) criteria for opioid dependence - Patients must be able to speak English - Be agreeable to and capable of signing the willing to sign a consent form and assent (parent or guardian must consent, minor must assent) Who Should NOT Join This Trial: - Non-English-speaking patients - Have a known sensitivity to buprenorphine or naloxone - Be physiologically dependent on alcohol, benzodiazepines, or other drugs of abuse that require immediate medical attention. Other substance use diagnoses are not exclusionary. - Have a medical condition that would, in the opinion of the study physician, make participation medically hazardous, including unstable cardiovascular disease, neurological deficits, trauma, acute hepatitis, stroke, and liver or renal disease) - Be acutely psychotic, severely depressed, and in need of inpatient treatment, or is an immediate suicide risk - Be a nursing or pregnant female Always talk to your doctor about whether this trial is right for you.