RECRUITINGINTERVENTIONAL
Effect of Inspiratory Muscle Training on Physiological Function and Clinical Outcomes After Lung Transplant
Effect of Inspiratory Muscle Training on Physiological Function and Clinical Outcomes After Lung Transplant: A Randomized Controlled Trial
About This Trial
The purpose of this research is to study the effect of training the inspiratory muscles (i.e. the muscle that allow you to breath-in) on exercise capacity, quality of life, and short-term clinical outcomes in patients post lung transplant.
Who May Be Eligible (Plain English)
Who May Qualify:
\- All patients who undergo single- or double-lung transplant at Mayo Clinic Florida.
Who Should NOT Join This Trial:
- Patients who do not survive the intra-operative period during the transplant surgery.
- Patients undergoing retransplantation.
- Patients undergoing multiorgan transplantation.
- Patients who are not willing to or who are unable to give written willing to sign a consent form.
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
\- All patients who undergo single- or double-lung transplant at Mayo Clinic Florida.
Exclusion Criteria:
* Patients who do not survive the intra-operative period during the transplant surgery.
* Patients undergoing retransplantation.
* Patients undergoing multiorgan transplantation.
* Patients who are not willing to or who are unable to give written informed consent.
Treatments Being Tested
DEVICE
POWERBreathe Plus®
Commercially available pressure-threshold device
OTHER
Cardiopulmonary rehabilitation post lung transplant
Pulmonary function, lung diffusing capacity for carbon monoxide, inspiratory muscle strength, and diaphragm dimensions will be assessed in each patient. Each patient will also undergo a cardiopulmonary exercise test (CPET), 6 minute walk test, and an inspiratory muscle endurance test
Locations (1)
Mayo Clinic in Florida
Jacksonville, Florida, United States