Skip to main content
TrialFinder
TrialFinder is for informational purposes only and does not provide medical advice. Always talk to your doctor about whether a trial is right for you.
RECRUITINGINTERVENTIONAL

Changes in Regional and Global Cardiac Contractility After Stimulation in Scar Zone with the NOGA System

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

Despite a decrease in voltage amplitude in post-infarction scar areas, greater voltage amplitudes are sometimes observed at the time of local extrasystoles mechanically induced by catheters. However, no study has investigated whether these electrical changes are associated with mechanical changes in local contractility. However, the voltage is closely correlated to the local contractile function as evidenced by the use of the NOGA system.

Who May Be Eligible (Plain English)

Who May Qualify: \- Patients who should undergo ventricular tachycardia (VT) ablation after a myocardial infarction according to current recommendations, namely: patients with ischemic heart disease (ICD) and with episodes of sustained ventricular tachycardia responsible for internal electric shocks by the implantable automatic defibrillator (ICD) (grade IB recommendation) OR - patients with an MIC and an ICD, presenting a first episode of sustained ventricular tachycardia (grade IIa, B recommendation) - Affiliated with a social protection scheme - Having signed an willing to sign a consent form Who Should NOT Join This Trial: - Contraindication or non-indication for ventricular tachycardia ablation - Women who are pregnant or of childbearing age and without contraception, breastfeeding women - Patients without ischemic heart disease - Patients under guardianship, curatorship or legal protection. Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: \- Patients who should undergo ventricular tachycardia (VT) ablation after a myocardial infarction according to current recommendations, namely: patients with ischemic heart disease (ICD) and with episodes of sustained ventricular tachycardia responsible for internal electric shocks by the implantable automatic defibrillator (ICD) (grade IB recommendation) OR * patients with an MIC and an ICD, presenting a first episode of sustained ventricular tachycardia (grade IIa, B recommendation) * Affiliated with a social protection scheme * Having signed an informed consent Exclusion Criteria: * Contraindication or non-indication for ventricular tachycardia ablation * Women who are pregnant or of childbearing age and without contraception, breastfeeding women * Patients without ischemic heart disease * Patients under guardianship, curatorship or legal protection.

Treatments Being Tested

DEVICE

NOGA TM probe

Each subject will be his own witness since the linear local shortening (LLS) will be measured successively in all patients before, then after stimulation of the scar zone (comparison of LLS measured in sinus rhythm then during stimulation in the scar zone for each patient. Each subject being his own witness and the two recordings being made a few minutes apart, during the same procedure.

Locations (1)

ROLLIN Anne
Toulouse, CHU de Toulouse, France