Effects of CPAP Therapy on Blood Pressure and Heart Rate Variability in Obstructive Sleep Apnea

Who May Qualify: - 30 to 75 years of age - Among patients with hypertension, no change in BP medication for at least 3 months. - Willing and able to give willing to sign a consent form - Willing and able to complete ambulatory blood pressure monitoring at baseline and after 6-months. - Sleep study \[Polysomnography (PSG) or Home Sleep Apnea Study (HSAT) performed based on clinical grounds - 4% oxygen desaturation index (ODI4) ≥15 events/hour on clinical sleep study - Planned CPAP treatment by treating provider Who Should NOT Join This Trial: - Unable to apply BP cuff (e.g. arm circumference \>55 cm, prior breast cancer, structural abnormalities of the arm) - Current use of CPAP or Dental Device for OSA - Category III-IV of heart failure - Presence of Cheyne-Stokes Respiration (CSR) in PSG - Predominantly central sleep apnea (AHI≥15 events/hour) - Pregnancy - History of renal failure, or renal transplant - Self-reported sleep duration less than 5 hours per night on weeknights (work nights) - Other sleep disorders - Use of supplemental oxygen during wakefulness or sleep - Self-reported illicit drug use or marijuana use more than once per week - Unstable medical conditions: uncontrolled angina, uncontrolled hypertension, severe chronic obstructive pulmonary disease, active cancer, or unstable psychiatric disease - Any underlying condition that, in the opinion of the lead investigator, prohibits participation in the study - Development or adoption of any of the above exclusion criteria during the study period Always talk to your doctor about whether this trial is right for you.