"Constitution of a Biological Collection to Establish Preclinical Translational Models for the Study of Tumors and Chronic Liver Diseases".

Who May Qualify: 1. Patients - diagnosed with chronic liver disease (viral or not) - diagnosed with at least one liver nodule for which a biopsy is planned as part of the care - for hepatobiliary surgery planned as part of care - for locoregional treatment for HCC is indicated 2. Patients able to receive and understand information relating to the study and give their written willing to sign a consent form 3. Patients affiliated to the French social security system Who Should NOT Join This Trial: 1. Minor patients 2. Patients under legal protection, 3. Patients subject to legal protection or unable to express their consent, 4. Patients in a situation of social fragility, 5. Pregnant or breastfeeding woman, 6. No signing of willing to sign a consent form. Always talk to your doctor about whether this trial is right for you.