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RECRUITINGOBSERVATIONAL

PRediction of DIverse Glucocorticoids ToxIcity OUtcomeS

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

To date, there is no available tool that allows, at individual level, determination of the probability to develop clinically relevant complications of prolonged glucocorticoid therapy. In patients with inflammatory rheumatic disorders requiring prolonged glucocorticoid therapy, such tool could be useful to adapt first-line treatment decisions (in daily practice and in future clinical trials). The main objective of the study is to identify routine clinical, biological and DXA baseline characteristics predictive of the occurrence of clinically relevant complications of glucocorticoid therapy at 1 year, in order to propose a predictive score.

Who May Be Eligible (Plain English)

Who May Qualify: - Life expectancy \> 1 year. - Indication to initiate prolonged glucocorticoid therapy at a dosage ≥ 15 mg/day for the treatment of an inflammatory rheumatic disease. - Initial treatment or relapse. - Previsional treatment duration \> 3 months. Who Should NOT Join This Trial: - Unable to consent. - Previous corticosteroid therapy in the last 3 months at a significant dosage (\> 5 mg per day). Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Life expectancy \> 1 year. * Indication to initiate prolonged glucocorticoid therapy at a dosage ≥ 15 mg/day for the treatment of an inflammatory rheumatic disease. * Initial treatment or relapse. * Previsional treatment duration \> 3 months. Exclusion Criteria: * Unable to consent. * Previous corticosteroid therapy in the last 3 months at a significant dosage (\> 5 mg per day).

Locations (11)

CHU d'Angers
Angers, France
CHRU de Brest
Brest, France
CHD Vendée
La Roche-sur-Yon, France
CH Le Mans
Le Mans, France
CH des Pays de Morlaix
Morlaix, France
CHU de Nantes
Nantes, France
CHR d'Orléans
Orléans, France
<CHU de Poitiers
Poitiers, France
CHIC Quimper
Quimper, France
Clinique St Exupéry
Toulouse, France
CHU de Tours
Tours, France