RECRUITINGOBSERVATIONAL
Ocular Microbiome and Immune System in Dry Eyes
Associations of the Ocular Microbiome and the Immune System in Dry Eye Disease
About This Trial
The primary objectives of this study are the characterization of the ocular microbiome as well as of the local immune system in participants with and without dry eye disease. Secondary objectives are the identification of differences in the ocular microbiome as well as in the immune system between participants with and without dry eye disease to ultimately find associations between the ocular microbiome and the immune system in dry eye disease.
Who May Be Eligible (Plain English)
Who May Qualify:
- Willing to sign willing to sign a consent form
- 18 years of age or older
Who Should NOT Join This Trial:
- Not willing or able to sign willing to sign a consent form
- Younger than 18 years
- Recent (3 month) history of use of systemic and/or topical antibiotics
- Usage of medical eye drops (Lacrycon and other moisturizing eye drops are allowed)
- Recent (3 month) history of ocular surgery
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Willing to sign informed consent
* 18 years of age or older
Exclusion Criteria:
* Not willing or able to sign informed consent
* Younger than 18 years
* Recent (3 month) history of use of systemic and/or topical antibiotics
* Usage of medical eye drops (Lacrycon and other moisturizing eye drops are allowed)
* Recent (3 month) history of ocular surgery
Treatments Being Tested
OTHER
Ocular microbiome
Taxonomical and functional characterization of the ocular microbiome
OTHER
Ocular immune system
Functional characterization of the tear fluid proteome, histology of conjunctival tissue and molecular assays
Locations (1)
Department of Ophthalmology, Inselspital
Bern, Switzerland