RECRUITINGOBSERVATIONAL
Biomarkers in the Brain Oxygen Optimization in Severe Traumatic Brain Injury Trial
Biomarkers in the Brain Oxygen Optimization in Severe Traumatic Brain Injury Trial (BioBOOST)
About This Trial
BioBOOST is a multicenter, observational study of the effect of derangements in brain physiologic parameters on brain injury biomarker levels in patients with severe traumatic brain injury.
Who May Be Eligible (Plain English)
Who May Qualify:
- Enrolled in BOOST-3 (this is an ancillary study to the BOOST-3 trial)
- BOOST-3 participant is enrolled at a BioBOOST site
- Able to maintain initial blood sample within 24 hours of injury
- Provide proxy willing to sign a consent form
Who Should NOT Join This Trial:
- Profoundly anemic (subjects who are profoundly anemic require blood transfusion)
- Age less than 18 years
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Enrolled in BOOST-3 (this is an ancillary study to the BOOST-3 trial)
* BOOST-3 participant is enrolled at a BioBOOST site
* Able to maintain initial blood sample within 24 hours of injury
* Provide proxy informed consent
Exclusion Criteria:
* Profoundly anemic (subjects who are profoundly anemic require blood transfusion)
* Age less than 18 years
Treatments Being Tested
OTHER
No intervention. This is an observational study.
There are no interventions being tested in the Bio-BOOST study.
Locations (2)
University of Michigan
Ann Arbor, Michigan, United States
Penn Presbyterian Medical Center
Philadelphia, Pennsylvania, United States