RECRUITINGINTERVENTIONAL
Optical Coherence Tomography Angiography in Subjects With Retinal Vascular Disease
About This Trial
This study will perform a prospective, longitudinal analysis of clinical and imaging findings from normal controls and subjects with retinal vascular disease to better define the diagnostic imaging criteria that signify change in disease stage. This includes disease progression in early stages of disease or disease regression with appropriate standard-of-care treatment.
Who May Be Eligible (Plain English)
Who Should NOT Join This Trial:
- Both subjects with diseases and controls:
- Children (age\<18)
- Pregnant females
- Developmentally delayed subjects
- Subjects unable to provide willing to sign a consent form
- Inability to cooperate with tests and study instructions
- Images with motion artifact or signal strength \< 7
- History of glaucoma
- History of age-related macular degeneration
- History of any visually significant eye disease
- History of proliferative diabetic retinopathy
- History of any inflammatory disease
- History of heart disease
- History of thyroid disease.
- Additional criteria for controls:
- History of any type of Diabetes Mellitus
- History of any type of Hypertension
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Exclusion Criteria:
* Both subjects with diseases and controls:
* Children (age\<18)
* Pregnant females
* Developmentally delayed subjects
* Subjects unable to provide informed consent
* Inability to cooperate with tests and study instructions
* Images with motion artifact or signal strength \< 7
* History of glaucoma
* History of age-related macular degeneration
* History of any visually significant eye disease
* History of proliferative diabetic retinopathy
* History of any inflammatory disease
* History of heart disease
* History of thyroid disease.
* Additional criteria for controls:
* History of any type of Diabetes Mellitus
* History of any type of Hypertension
Treatments Being Tested
DEVICE
Swept-Source (SS) OCT Angiography
Non-invasive, minimal risk, ocular imaging study
DEVICE
Spectral-Domain (SD) OCT Angiography
Non-invasive, minimal risk, ocular imaging study
DEVICE
Fundus Imaging
Non-invasive, minimal risk, ocular imaging study
DEVICE
Axial Length Measurement Device
Non-invasive, minimal risk, ocular imaging study
Locations (1)
Wilmer Eye Institute
Baltimore, Maryland, United States