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RECRUITINGOBSERVATIONAL

Influenza Vaccination, ACEI and ARB in the Evolution of SARS-CoV2 Infection

Evaluation of Influenza Vaccination and Treatment With ACEI and ARB in the Evolution of SARS-CoV2 Infection

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

Some authors have proposed the use of the flu vaccine to reduce the severity of COVID-19 cases, while some have proposed the use of ACE Inhibitors (ACEI) or Angiotensin Receptor blockers (ARB), since this virus shares hemagglutinin as a transmission mechanism and acts on the ACE2 enzyme during infection. Other authors described how none of the elderly patients receiving antihistamines and azythromycin in two nursing homes in Toledo -Spain- during the first wave died or needed hospital admission, even considering that 100% of residents had a positive serological test after that wave. Other authors have described a positive evolution in patients receiving amantadine for their Parkinson's disease. The aim is to evaluate whether the admitted patients who are previously vaccinated or those who were already receiving these treatments showed a better evolution.

Who May Be Eligible (Plain English)

Who May Qualify: - Hospital Admissions at the Hospital of Terrassa from March 1, 2020 for any cause. Who Should NOT Join This Trial: - None. - For comparison of percentage of Influenza vaccination, ACEI and ARB vs general population, patients from outside the reference area of the Terrassa Health Consortium would be excluded. Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Hospital Admissions at the Hospital of Terrassa from March 1, 2020 for any cause. Exclusion Criteria: * None. * For comparison of percentage of Influenza vaccination, ACEI and ARB vs general population, patients from outside the reference area of the Terrassa Health Consortium would be excluded.

Treatments Being Tested

DRUG

Antihistamine

No intervention is performed. We propose an observational study.

DRUG

Amantadine

No intervention is performed. We propose an observational study

DRUG

ACEI

No intervention is performed. We propose an observational study.

DRUG

ARB

No intervention is performed. We propose an observational study.

OTHER

Influenza vaccine and COVID

No intervention is performed. We propose an observational study.

Locations (1)

Hospital de Terrassa
Terrassa, Barcelona, Spain