RaDiCo PID Cohort (RaDiCo-ILD Cohort in English)

Who May Qualify: - Clinical criteria: chronic respiratory insufficiency manifestations including dyspnea/tachypnea, cough, and cyanosis during exercise or at rest - Radiological criteria: characteristic chest High-Resolution Computed Tomography (HRCT) abnormalities including widespread ground glass or alveolar attenuation, reticulation often associated with traction bronchiectasis, and honeycombing - Functional criteria: pulmonary function test abnormalities reflecting a restrictive pattern and including: loss of lung volume, vital capacity (VC), total lung capacity (TLC); reduction in the diffusion capacity of the lung for carbon monoxide (DLCO), gas exchange abnormalities, and altered ventilatory response to exercise - Patients (parents/guardians for paediatric/patients) having given an willing to sign a consent form to participate in the protocol - Patients affiliated to the "Regime National d'Assurance Maladie" Who Should NOT Join This Trial: - Patients with diffuse parenchymal lung diseases caused by drug toxicity, weakened immune system, proliferative disorders including histiocytosis, and metabolic disorders - Patients (parents/guardians for paediatric patient) not able to approve/understand the protocol Always talk to your doctor about whether this trial is right for you.