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RECRUITINGOBSERVATIONAL

Pregnancy in Women With Rare Multisystemic Vascular Diseases: COGRare5 Study

A National Prospective Cohort for Pregnancies in Patients With Rare Vascular Anomalies: COGRare5 Study

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

There are no prospective studies of pregnancies for the diseases studied here in (Heredity Hemorrhagic Telangiectasia, Marfan syndrome or related, primary lower limb lymphedema, superficial arteriovenous malformations, and cerebro-spinal arteriovenous malformations) although complications of these can present life-threatening health problems for the mother and her baby. The purpose of this National prospective study is to obtain greater insight into obstetrical complications associated with rare maternal vascular genetic disorders in order to improve prevention and to reduce risk of death. In this context, experts and patient associations consider that there is a need to make real progress in the formulation of recommendations based on scientific data.

Who May Be Eligible (Plain English)

Who May Qualify: - Women aged ≥ 18 years and ≤45 years at the time of inclusion - Pregnant and/or having given birth less than 1 month (≤ 30 days) - Clinically and/or radiological and/or molecular biology diagnosis of a rare vascular disease before or during pregnancy or one month after delivery. - Having been informed of all pertinent aspects of the study and provided oral non-opposition. Who Should NOT Join This Trial: - Any person not fulfilling the inclusion criteria or refusing to take part in the study. - Major under legal protection Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Women aged ≥ 18 years and ≤45 years at the time of inclusion * Pregnant and/or having given birth less than 1 month (≤ 30 days) * Clinically and/or radiological and/or molecular biology diagnosis of a rare vascular disease before or during pregnancy or one month after delivery. * Having been informed of all pertinent aspects of the study and provided oral non-opposition. Exclusion Criteria: * Any person not fulfilling the inclusion criteria or refusing to take part in the study. * Major under legal protection

Treatments Being Tested

OTHER

Questionnaire

Interview of women with a rare vascular disease through a phone questionnaire about severe and specific obstetrical complications during and after pregnancy.

Locations (20)

Service de Médecine Interne et Maladies Vasculaires + Service Neuropédiatrie et neurochirurgie de l'enfant - CHU Angers
Angers, France
Service de Médecine interne et immunologie clinique + Service de Médecine Vasculaire - Hôpital Saint André, CHU de Bordeaux
Bordeaux, France
Service Pneumologie et Oncologie Thoracique - AP-HP Hôpital Ambroise Paré
Boulogne-Billancourt, France
Centre de Référence pour la maladie de Rendu-Osler - Service Génétique Clinique - Hôpital Femme-Mère-Enfant - Hospices Civils de Lyon
Bron, France
Service d'imagerie médicale - Neuroradiologie interventionnelle - Hôpital Neurologique P. Wertheimer - HCL
Bron, France
Service d'Imagerie Pédiatrique et Fœtale et Consultation Pluridisciplinaire des Angiomes - Hôpital Femme-Mère-Enfant - HCL
Bron, France
Service de Génétique, Hôpital Femme-Mère-Enfant
Bron, France
Service de Médecine Vasculaire - Hôpital de la Côte de Nacre
Caen, France
Service Médecine Interne Estaing CHU de Clermont-Ferrand - Hôpital d'Estaing
Clermont-Ferrand, France
CHU Dijon Bourgogne - Hôpital François Mitterrand
Dijon, France
Service de Médecine vasculaire et HTA - Hôpital Albert Calmette, CHRU de Lille
Lille, France
Service Médecine interne - CHRU de Lille - Hôpital Claude Huriez
Lille, France
CHU de Marseille - Hôpital de la Timone
Marseille, France
Service Médecine Interne - Hôpital Saint-Eloi, CHU de Montpellier
Montpellier, France
Service de neuroradiologie diagnostique et interventionnelle - CHU de Nancy, Hôpital St-Julien
Nancy, France
Service de Médecine Interne-Médecine Vasculaire, CHU de Nantes - Hôtel Dieu
Nantes, France
Unité de neuro-interventionnelle CHU Nice, Hôpital Pasteur 2
Nice, France
Service de dermatologie, CHU de Nice - Hôpital l'Archet 2
Nice, France
Service de Neuroradiologie - AP-HP - Paris (Hôpital Lariboisière)
Paris, France
Service de Lymphologie - Hôpital Cognacq-Jay - Paris
Paris, France