RECRUITINGOBSERVATIONAL
IBD Registry in a Sub-Saharan African Population
Registry to Study the Incidence, Phenotype, Risk Factors and Clinical Course of Inflammatory Bowel Disease in Zimbabwe
About This Trial
The investigators intend to establish a prospective registry of patients diagnosed with inflammatory bowel disease at Parirenyatwa hospital in Harare, Zimbabwe. The study will periodically collect data on disease phenotype, disease course, and clinical management, and will biobank stool specimens and germline DNA. One relative, and an individual from the same neighbourhood will be also be recruited for a nested case-control study into risk factors of inflammatory bowel disease in this population.
Who May Be Eligible (Plain English)
Who May Qualify:
- Cases
1. Any patient with confirmed inflammatory bowel disease
2. Onset of disease ≥3 months ago.
- Controls
1. Age ≥ 18 years (NB - cases younger than 18 will be excluded from case-control analysis
2. One sibling or cousin (2nd degree) and one neighbourhood control.
Who Should NOT Join This Trial:
- Cases
1\. None
- Controls
1. Suspected inflammatory bowel disease
2. Unexplained gastrointestinal symptoms including diarrhoea, vomiting, chronic abdominal pain, weight loss, rectal bleeding, and recent change in bowel habit.
3. Previous unexplained gastrointestinal surgery
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Cases
1. Any patient with confirmed inflammatory bowel disease
2. Onset of disease ≥3 months ago.
* Controls
1. Age ≥ 18 years (NB - cases younger than 18 will be excluded from case-control analysis
2. One sibling or cousin (2nd degree) and one neighbourhood control.
Exclusion Criteria:
* Cases
1\. None
* Controls
1. Suspected inflammatory bowel disease
2. Unexplained gastrointestinal symptoms including diarrhoea, vomiting, chronic abdominal pain, weight loss, rectal bleeding, and recent change in bowel habit.
3. Previous unexplained gastrointestinal surgery
Treatments Being Tested
OTHER
No intervention
No intervention
Locations (1)
Parirenyatwa Hospital
Harare, Zimbabwe