Stereotactic Magnetic Resonance Guided Radiation Therapy

Who May Qualify: - Participants must have a confirmed malignancy requiring stereotactic body radiation therapy. See specific disease site cohorts for more details. - Tumor size ≤ 7cm - Age 18 years of older. - ECOG performance status ≤2 (Karnofsky ≥60%, see Appendix A) - Ability to understand and the willingness to sign a written willing to sign a consent form document. - Specific eligibility requirements for each disease site with be covered in each specific cohort. Who Should NOT Join This Trial: - Specific exclusion requirements for each disease site with be covered in each specific cohort - History of allergic reactions attributed to gadolinium-based IV contrast. \-- Note: If a patient will not receive contrast, this is not applicable - Pregnant women are excluded from this study. - Severe claustrophobia or anxiety - Participants who cannot undergo an MRI Always talk to your doctor about whether this trial is right for you.