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RECRUITINGPhase 2INTERVENTIONAL

Focal HDR Brachytherapy Boost to Stereotactic Radiotherapy

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

To determine if fBT+sRT is superior to standard care in terms of urinary toxicity by having fewer patients experience a minimal important decline (MID) in urinary irritation/obstructive QoL

Who May Be Eligible (Plain English)

Who May Qualify: - Histological diagnosis of prostate cancer planned for curative-intent HDR brachytherapy boost to external beam radiotherapy to the prostate gland. - ECOG 0-1 - Charlson Comorbidity Index ≤ 4 - Imaging visible disease encompassing \< 50% of the prostate gland and consistent with biopsy findings. Exclusion - none Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Histological diagnosis of prostate cancer planned for curative-intent HDR brachytherapy boost to external beam radiotherapy to the prostate gland. * ECOG 0-1 * Charlson Comorbidity Index ≤ 4 * Imaging visible disease encompassing \< 50% of the prostate gland and consistent with biopsy findings. Exclusion - none

Treatments Being Tested

RADIATION

focal brachytherapy boost to SBRT

As above

Locations (2)

Centre Hospitalier de l'Université de Montréal
Montreal, Quebec, Canada
CHUQ
Québec, Quebec, Canada