RECRUITINGOBSERVATIONAL
The FOrMe Registry (The German Focal Segmental Glomerulosclerosis and Minimal Change Disease Registry)
About This Trial
In a monocentric, later multicentric prospective approach the FOrMe registry (The German Focal Segmental Glomerulosclerosis and Minimal Change Disease Registry) aims to generate a longitudinal cohort of 150 pediatric cases of idiopathic nephrotic syndrome and 350 adult cases of biopsy-proven Minimal Change Disease (MCD) or Focal and Segmental Glomerular Sclerosis (FSGS) over 10 years. The registry will provide a repository for biomaterials such as blood samples, DNA, urine, feces, and tissue biopsies that will be accessible to collaborators to facilitate future research on pathogenesis, diagnostics, and treatment.
Who May Be Eligible (Plain English)
Inclusion Criteria (cohort A):
- written willing to sign a consent form
- 17 or less years of age
- idiopathic nephrotic syndrome
Inclusion Criteria (cohort B):
- written willing to sign a consent form
- older or equal to 18 years of age
- biopsy-proven primary or secondary FSGS or MCD or biopsy-proven recurrence of disease in kidney transplant.
Exclusion Criteria (both cohorts):
- Prior kidney transplant without biopsy-proven recurrence
- A clinical diagnosis of other glomerular disease resulting in secondary MCD or FSGS as judged by the treating physicians.
- Refusal to provide written willing to sign a consent form
- (Anticipated) incompliance with visit schedule
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria (cohort A):
* written informed consent
* 17 or less years of age
* idiopathic nephrotic syndrome
Inclusion Criteria (cohort B):
* written informed consent
* older or equal to 18 years of age
* biopsy-proven primary or secondary FSGS or MCD or biopsy-proven recurrence of disease in kidney transplant.
Exclusion Criteria (both cohorts):
* Prior kidney transplant without biopsy-proven recurrence
* A clinical diagnosis of other glomerular disease resulting in secondary MCD or FSGS as judged by the treating physicians.
* Refusal to provide written informed consent
* (Anticipated) incompliance with visit schedule
Treatments Being Tested
OTHER
Biosampling
Biosampling at initial visit and follow-up visits
Locations (12)
University Hospital of Cologne
Cologne, North Rhine-Westphalia, Germany
Uniklinik RWTH Aachen
Aachen, Germany
Charité University Hospital
Berlin, Germany
Kindernierenzentrum Bonn
Bonn, Germany
Kindernephrologie Dachau
Dachau, Germany
University Hospital Erlangen
Erlangen, Germany
University Hospital Essen
Essen, Germany
University Hospital Heidelberg
Heidelberg, Germany
Klinikum St. Georg
Leipzig, Germany
University Hospital Marburg
Marburg, Germany
University Hospital Münster
Münster, Germany
Klinikum Stuttgart
Stuttgart, Germany