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RECRUITINGOBSERVATIONAL

Detection of Unsuspected Small Airways Obstruction in Cystic Fibrosis

The Measurement and Analysis of Maximal Expiratory Flow Volume Loops at Low Lung Volumes in Children With Cystic Fibrosis and Normal Routine Lung Function.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

Goal is to physiologically detect unsuspected small airways obstruction in children and adults with treated heterozygous and homozygous cystic fibrosis. Unsuspected refers to normal routine pre bronchodilator spirometry including normal FEV1(L), FVC (L). and FEV1/FVC%. This is a retrospective study.

Who May Be Eligible (Plain English)

Who May Qualify: Heterozygote or homozygote patients with cystic fibrosis with normal routine pre bronchodilator spirometry including normal FEV1(L), FVC(L) and FEV1/FVC%. Who Should NOT Join This Trial:Heterozygote or homozygote patients with cystic fibrosis with ABNORMAL routine pre bronchodilator spirometry \- Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: Heterozygote or homozygote patients with cystic fibrosis with normal routine pre bronchodilator spirometry including normal FEV1(L), FVC(L) and FEV1/FVC%. Exclusion Criteria:Heterozygote or homozygote patients with cystic fibrosis with ABNORMAL routine pre bronchodilator spirometry \-

Treatments Being Tested

DIAGNOSTIC_TEST

spirometry

measure spirometry and lung CT

Locations (2)

Arthur F Gelb MD
Lakewood, California, United States
Miller Children's Hospital and Long Beach Medical Center
Long Beach, California, United States