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RECRUITINGPhase 2INTERVENTIONAL

Efficacy of Nitrous Oxide in OCD: Pilot Study

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

This study investigates whether the commonly used and well-tolerated inhaled anesthetic nitrous oxide can rapidly improve symptoms of OCD.

Who May Be Eligible (Plain English)

Who May Qualify: - Age 18-65 - Primary diagnosis of OCD - Sufficient severity of OCD symptoms - Ability to tolerate a treatment-free period - Capacity to provide willing to sign a consent form Who Should NOT Join This Trial: - Psychiatric or medical conditions that make participation unsafe - Pregnant or nursing females - Concurrent use of any medications that might increase the risk of participation (e.g. drug interactions) Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Age 18-65 * Primary diagnosis of OCD * Sufficient severity of OCD symptoms * Ability to tolerate a treatment-free period * Capacity to provide informed consent Exclusion Criteria: * Psychiatric or medical conditions that make participation unsafe * Pregnant or nursing females * Concurrent use of any medications that might increase the risk of participation (e.g. drug interactions)

Treatments Being Tested

DRUG

Nitrous Oxide

OCD participants in this arm will receive 50%oxygen/50% nitrous oxide admixture for 60 minutes.

DRUG

Nitrogen

OCD participants in this arm will receive 50%oxygen/50% nitrogen admixture for 60 minutes.

Locations (1)

Stanford University
Stanford, California, United States