RECRUITINGINTERVENTIONAL
IDENTIFICATION OF PROGNOSTIC AND PREDICTIVE BIOMARKERS IN INFLAMMATORY BOWEL DISEASE
IDENTIFICATION OF PROGNOSTIC AND PREDICTIVE BIOMARKERS OF NATURAL HISTORY AND RESPONSE TO BIOTHERAPIES IN INFLAMMATORY BOWEL DISEASE : i-BANK
About This Trial
Interventional study of a group of patients with an inflammatory bowel disease (IBD; Crohn's disease (CD) or ulcerative colitis (UC)) to identify predictive and prognostic biomarkers of natural history and response to biotherapies.
Who May Be Eligible (Plain English)
Who May Qualify:
- Age\>=18 years
- Patients with an established diagnosis of CD or UC (clinical, biological, radiological, endoscopic or histologic criteria)
- Patients \>=45 kg
- Affiliated member of the Social Security system
Who Should NOT Join This Trial:
- Patients with an undetermined colitis
- Patients with a non established diagnosis of CD
- Women of childbearing age without a method of contraception
- Persons covered by articles L. 1121-5, L. 1121-7 and L1121-8 of the Public Health Code
- Pregnant women, breastfeeding women
\-- Age \< 18 years
- Persons under legal protection
- Person who does not have the capacity to consent
- Persons under the age of 18 years who are deprived of their liberty by decision of a judicial or administrative authority (articles L. 3212-1 and L. 3213-1).
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Age\>=18 years
* Patients with an established diagnosis of CD or UC (clinical, biological, radiological, endoscopic or histologic criteria)
* Patients \>=45 kg
* Affiliated member of the Social Security system
Exclusion Criteria:
* Patients with an undetermined colitis
* Patients with a non established diagnosis of CD
* Women of childbearing age without a method of contraception
* Persons covered by articles L. 1121-5, L. 1121-7 and L1121-8 of the Public Health Code
* Pregnant women, breastfeeding women
\-- Age \< 18 years
* Persons under legal protection
* Person who does not have the capacity to consent
* Persons under the age of 18 years who are deprived of their liberty by decision of a judicial or administrative authority (articles L. 3212-1 and L. 3213-1).
Treatments Being Tested
PROCEDURE
endoscopic biopsy
Per-endoscopic biopsies
PROCEDURE
samples of the oral cavity
7 samples of the oral cavity with a swab
PROCEDURE
Samples of the resected specimen
if patient has to undergo a digestive resection as part of his standard management, samples of the pathological area and samples at the end of the resection will be realised
Locations (1)
CHRU Nancy
Vandœuvre-lès-Nancy, France