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RECRUITINGINTERVENTIONAL

IDENTIFICATION OF PROGNOSTIC AND PREDICTIVE BIOMARKERS IN INFLAMMATORY BOWEL DISEASE

IDENTIFICATION OF PROGNOSTIC AND PREDICTIVE BIOMARKERS OF NATURAL HISTORY AND RESPONSE TO BIOTHERAPIES IN INFLAMMATORY BOWEL DISEASE : i-BANK

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

Interventional study of a group of patients with an inflammatory bowel disease (IBD; Crohn's disease (CD) or ulcerative colitis (UC)) to identify predictive and prognostic biomarkers of natural history and response to biotherapies.

Who May Be Eligible (Plain English)

Who May Qualify: - Age\>=18 years - Patients with an established diagnosis of CD or UC (clinical, biological, radiological, endoscopic or histologic criteria) - Patients \>=45 kg - Affiliated member of the Social Security system Who Should NOT Join This Trial: - Patients with an undetermined colitis - Patients with a non established diagnosis of CD - Women of childbearing age without a method of contraception - Persons covered by articles L. 1121-5, L. 1121-7 and L1121-8 of the Public Health Code - Pregnant women, breastfeeding women \-- Age \< 18 years - Persons under legal protection - Person who does not have the capacity to consent - Persons under the age of 18 years who are deprived of their liberty by decision of a judicial or administrative authority (articles L. 3212-1 and L. 3213-1). Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Age\>=18 years * Patients with an established diagnosis of CD or UC (clinical, biological, radiological, endoscopic or histologic criteria) * Patients \>=45 kg * Affiliated member of the Social Security system Exclusion Criteria: * Patients with an undetermined colitis * Patients with a non established diagnosis of CD * Women of childbearing age without a method of contraception * Persons covered by articles L. 1121-5, L. 1121-7 and L1121-8 of the Public Health Code * Pregnant women, breastfeeding women \-- Age \< 18 years * Persons under legal protection * Person who does not have the capacity to consent * Persons under the age of 18 years who are deprived of their liberty by decision of a judicial or administrative authority (articles L. 3212-1 and L. 3213-1).

Treatments Being Tested

PROCEDURE

endoscopic biopsy

Per-endoscopic biopsies

PROCEDURE

samples of the oral cavity

7 samples of the oral cavity with a swab

PROCEDURE

Samples of the resected specimen

if patient has to undergo a digestive resection as part of his standard management, samples of the pathological area and samples at the end of the resection will be realised

Locations (1)

CHRU Nancy
Vandœuvre-lès-Nancy, France