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RECRUITINGINTERVENTIONAL

Comparing the Efficacy of Steroid, Acupuncture and Platelet Rich Plasma Injection in Patients with Sciatica

Comparing the Efficacy of Transforaminal Epidural Injections, Acupuncture and Platelet Rich Plasma Injection in Patients with Sciatica Due to Intervertebral Disc Herniation, Spinal Stenosis and Spondylolisthesis

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

Disc herniation, stenosis of the spine and spondylolisthesis are the common causes of radiculitis in medical practice today, and can cause symptoms of sciatica. Steroid injection, acupuncture and platelet-rich plasma injection are often used interventions for the treatments of sciatica. The investigators will investigate the efficacy and safety of steroid injection, acupuncture and platelet-rich plasma injection for sciatica in this single center, parallel, randomized-controlled clinical trial.

Who May Be Eligible (Plain English)

Who May Qualify: 1. Female or male, 20 to 80 years of age. 2. Participants who had dermatome between L3 to S1, or participants whose straight leg raising test was positive, or participants had Meyerding Grade I to II spondylolisthesis or herniated intervertebral disc or spinal stenosis diagnosed by X-rays, Magnetic resonance imaging or computed tomography. 3. Participants whose sciatica symptom doesn't have occur time limit. 4. Participants who agreed to follow the trial protocol. 5. Participants who could complete the study treatment and assessments. 6. Participants who had steroid or pain control injection can participate the study after receiving injection more than 3 days. Who Should NOT Join This Trial: 1. Participants with severe progressive neurological symptoms (e.g. cauda equina compression). 2. Participants who had undergone surgery for lumbar disc herniation within 6 months. 3. Participants whose sciatica symptom wasn't caused by lumbar radiculopathy. 4. Participants with cardiovascular, liver, kidney, or hematopoietic system diseases, severe psychiatric or psychological disorder, or cancer. 5. Women who were pregnant. 6. Participants with a pacemaker, metal allergy, or severe fear of needles. Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: 1. Female or male, 20 to 80 years of age. 2. Participants who had dermatome between L3 to S1, or participants whose straight leg raising test was positive, or participants had Meyerding Grade I to II spondylolisthesis or herniated intervertebral disc or spinal stenosis diagnosed by X-rays, Magnetic resonance imaging or computed tomography. 3. Participants whose sciatica symptom doesn't have occur time limit. 4. Participants who agreed to follow the trial protocol. 5. Participants who could complete the study treatment and assessments. 6. Participants who had steroid or pain control injection can participate the study after receiving injection more than 3 days. Exclusion Criteria: 1. Participants with severe progressive neurological symptoms (e.g. cauda equina compression). 2. Participants who had undergone surgery for lumbar disc herniation within 6 months. 3. Participants whose sciatica symptom wasn't caused by lumbar radiculopathy. 4. Participants with cardiovascular, liver, kidney, or hematopoietic system diseases, severe psychiatric or psychological disorder, or cancer. 5. Women who were pregnant. 6. Participants with a pacemaker, metal allergy, or severe fear of needles.

Treatments Being Tested

OTHER

Steroid

Triamcinolone 1pc + lidocaine 1% 1cc inject at neuritis nerve roots

OTHER

Acupuncture

1.5 inch acupuncture needles insert at acupoints BL23, BL24, BL25 and BL26

OTHER

Platelet Rich Plasma

Inject investigators Platelet Rich Plasma at neuritis nerve roots

Locations (1)

Taipei Medical University Hospital
Taipei, Taiwan, Taiwan