RECRUITINGOBSERVATIONAL
Lifetime Endurance Exercise to Prevent Coronary Artery Disease
Lifetime Endurance Exercise to Prevent Coronary Artery Disease. A Comparison With Late-onset Endurance Training and a Sedentary Lifestyle
About This Trial
The primary objective of the Master@Heart Trial is to investigate whether lifelong endurance exercise reduces the incidence of non-calcified plaques (both mixed and soft plaques) as compared to late-onset endurance exercise and a non-athletic lifestyle.
Who May Be Eligible (Plain English)
Who May Qualify:
- Lifelong endurance athletes:
- Initiation of endurance sports before the age of 30 years
- Activities at regional, national or international level
- Sports: triathlon, cycling, distance running (1500 metres and longer) and rowing
- Aged 45-70 years
- Involved in competition and high-level training:
- more than 10 hours per week for cyclists and triathletes
- more than 6 hours per week for runners and rowers.
- Late-onset endurance athletes:
- Initiation of endurance sports after the age of 30 years and at least 6 months ago
- Activities at regional, national or international level
- Sports: triathlon, cycling, distance running (1500 metres and longer) and rowing
- Aged 45-70 years
- Involved in competition and high-level training:
- more than 10 hours per week for cyclists and triathletes
- more than 6 hours per week for runners and rowers.
- Healthy non-athletes
- subjects seen in the outpatient clinic for a work-related medical check-up
- university alumni
- subjects from multisports organisations
- history of regular sports practice \<3 hours /week
- participation in regular sports with a low dynamic component (e.g. billiards, darts or bowling) \>3 hours /week is allowed
Who Should NOT Join This Trial:
- history of smoking (\> 5 pack years)
- history of diabetes
- diagnosis of cardiopulmonary disorder prior to inclusion
- medical treatment for arterial hypertension or hypercholesterolemia
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Lifelong endurance athletes:
* Initiation of endurance sports before the age of 30 years
* Activities at regional, national or international level
* Sports: triathlon, cycling, distance running (1500 metres and longer) and rowing
* Aged 45-70 years
* Involved in competition and high-level training:
* more than 10 hours per week for cyclists and triathletes
* more than 6 hours per week for runners and rowers.
* Late-onset endurance athletes:
* Initiation of endurance sports after the age of 30 years and at least 6 months ago
* Activities at regional, national or international level
* Sports: triathlon, cycling, distance running (1500 metres and longer) and rowing
* Aged 45-70 years
* Involved in competition and high-level training:
* more than 10 hours per week for cyclists and triathletes
* more than 6 hours per week for runners and rowers.
* Healthy non-athletes
* subjects seen in the outpatient clinic for a work-related medical check-up
* university alumni
* subjects from multisports organisations
* history of regular sports practice \<3 hours /week
* participation in regular sports with a low dynamic component (e.g. billiards, darts or bowling) \>3 hours /week is allowed
Exclusion Criteria:
* history of smoking (\> 5 pack years)
* history of diabetes
* diagnosis of cardiopulmonary disorder prior to inclusion
* medical treatment for arterial hypertension or hypercholesterolemia
Locations (3)
University Hospital, Antwerpen
Edegem, Belgium
Jessa Hospital
Hasselt, Belgium
UZLeuven
Leuven, Belgium