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RECRUITINGOBSERVATIONAL

Lifetime Endurance Exercise to Prevent Coronary Artery Disease

Lifetime Endurance Exercise to Prevent Coronary Artery Disease. A Comparison With Late-onset Endurance Training and a Sedentary Lifestyle

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About This Trial

The primary objective of the Master@Heart Trial is to investigate whether lifelong endurance exercise reduces the incidence of non-calcified plaques (both mixed and soft plaques) as compared to late-onset endurance exercise and a non-athletic lifestyle.

Who May Be Eligible (Plain English)

Who May Qualify: - Lifelong endurance athletes: - Initiation of endurance sports before the age of 30 years - Activities at regional, national or international level - Sports: triathlon, cycling, distance running (1500 metres and longer) and rowing - Aged 45-70 years - Involved in competition and high-level training: - more than 10 hours per week for cyclists and triathletes - more than 6 hours per week for runners and rowers. - Late-onset endurance athletes: - Initiation of endurance sports after the age of 30 years and at least 6 months ago - Activities at regional, national or international level - Sports: triathlon, cycling, distance running (1500 metres and longer) and rowing - Aged 45-70 years - Involved in competition and high-level training: - more than 10 hours per week for cyclists and triathletes - more than 6 hours per week for runners and rowers. - Healthy non-athletes - subjects seen in the outpatient clinic for a work-related medical check-up - university alumni - subjects from multisports organisations - history of regular sports practice \<3 hours /week - participation in regular sports with a low dynamic component (e.g. billiards, darts or bowling) \>3 hours /week is allowed Who Should NOT Join This Trial: - history of smoking (\> 5 pack years) - history of diabetes - diagnosis of cardiopulmonary disorder prior to inclusion - medical treatment for arterial hypertension or hypercholesterolemia Always talk to your doctor about whether this trial is right for you.

Original Eligibility Criteria

View original clinical language
Inclusion Criteria: * Lifelong endurance athletes: * Initiation of endurance sports before the age of 30 years * Activities at regional, national or international level * Sports: triathlon, cycling, distance running (1500 metres and longer) and rowing * Aged 45-70 years * Involved in competition and high-level training: * more than 10 hours per week for cyclists and triathletes * more than 6 hours per week for runners and rowers. * Late-onset endurance athletes: * Initiation of endurance sports after the age of 30 years and at least 6 months ago * Activities at regional, national or international level * Sports: triathlon, cycling, distance running (1500 metres and longer) and rowing * Aged 45-70 years * Involved in competition and high-level training: * more than 10 hours per week for cyclists and triathletes * more than 6 hours per week for runners and rowers. * Healthy non-athletes * subjects seen in the outpatient clinic for a work-related medical check-up * university alumni * subjects from multisports organisations * history of regular sports practice \<3 hours /week * participation in regular sports with a low dynamic component (e.g. billiards, darts or bowling) \>3 hours /week is allowed Exclusion Criteria: * history of smoking (\> 5 pack years) * history of diabetes * diagnosis of cardiopulmonary disorder prior to inclusion * medical treatment for arterial hypertension or hypercholesterolemia

Locations (3)

University Hospital, Antwerpen
Edegem, Belgium
Jessa Hospital
Hasselt, Belgium
UZLeuven
Leuven, Belgium